FIXED OIL DERIVED FROM Caryocar coriaceum (PEQUI FRUIT) PREVENTS TISSUE AND FUNCTIONAL ALTERATIONS IN THE RESPIRATORY SYSTEM INDUCED HOUSEHOLD AIR POLLUTION ORIGINATING FROM BIOMASS

Allison Matias de Sousa; Fladimir de Lima Gondim; Gilvan Ribeiro dos Santos; Marcelle Ferreira Moura; Ruth Mesquita Ferreira; Daniel Silveira Serra; Antônia Torres Ávila Pimenta; Mona Lisa Moura de Oliveira; Francisco Sales Ávila Cavalcante

doi:10.32435/envsmoke-2023-0019

Autores

Allison Matias de Sousa State University of Ceará https://orcid.org/0000-0001-5229-9823
Fladimir de Lima Gondim Federal University of Ceará https://orcid.org/0000-0002-3702-1003
Gilvan Ribeiro dos Santos Federal University of Ceará https://orcid.org/0009-0005-7879-0633
Marcelle Ferreira Moura Federal University of Ceará https://orcid.org/0000-0003-4988-9050
Ruth Mesquita Ferreira State University of Ceará https://orcid.org/0000-0001-6845-5309
Daniel Silveira Serra State University of Ceará https://orcid.org/0000-0002-5172-5824
Antônia Torres Ávila Pimenta Federal University of Ceará https://orcid.org/0000-0002-1191-0363
Mona Lisa Moura de Oliveira State University of Ceará https://orcid.org/0000-0001-9301-4134
Francisco Sales Ávila Cavalcante State University of Ceará https://orcid.org/0000-0003-4501-8119

DOI:

https://doi.org/10.32435/envsmoke-2023-0019

Palavras-chave:

Caryocar coriaceum, Pequi, Biomass, Household air, Indoor pollution, Asthma, Respiratory mechanics

Resumo

The reuse of biomass residue can be in different ways, such as pellets obtained through the compaction of green coconut shell. Despite the advantages, studies relate the burning of biomass as the main source of household air pollution. Indoor pollution is also correlated with serious consequences for groups considered at risk, such as asthmatics. As a result, the population is looking for alternative and low-cost treatments through natural products with anti-inflammatory characteristics, such as the fixed oil of Caryocar coriaceum (CC). In the present study, we evaluated the effects of oral CC ingestion on the respiratory system of mice submitted to a model of chronic exposure to smoke from the combustion of coconut shell pellets (CSP) and submitted to the OVA-induced asthma model. We performed analysis of the gaseous composition in the exposure chamber and analyzes of different aspects of the respiratory system. CC could prevent inflammatory cell infiltration and alveolar collapse. Furthermore, it was able to avoid changes in the airway resistance, tissue resistance, elastance, compliance and inspiratory capacity. Our findings demonstrate the effects of long-term exposure to indoor pollution and suggest that dietary intake of CC may be a strategy to prevent respiratory diseases.

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Biografia do Autor

Allison Matias de Sousa, State University of Ceará

Instituto Superior de Ciências Biomédicas, State University of Ceará, CEP: 60714-110, Fortaleza, Ceará, Brazil

Fladimir de Lima Gondim, Federal University of Ceará

Departamento de Química Orgânica e Inorgânica, Federal University of Ceará, CEP: 60.440-900, Fortaleza, Ceará, Brazil

Gilvan Ribeiro dos Santos, Federal University of Ceará

Departamento de Física, Federal University of Ceará, CEP: 60440-900, Fortaleza, Ceará, Brazil

Marcelle Ferreira Moura, Federal University of Ceará

Departamento de Física, Federal University of Ceará, CEP: 60440-900, Fortaleza, Ceará, Brazil

Ruth Mesquita Ferreira, State University of Ceará

Centro de Ciência e Tecnologia, State University of Ceará, CEP: 60741-000, Fortaleza, Ceará, Brazil

Daniel Silveira Serra, State University of Ceará

Centro de Ciência e Tecnologia, State University of Ceará, CEP: 60741-000, Fortaleza, Ceará, Brazil

Antônia Torres Ávila Pimenta, Federal University of Ceará

Departamento de Química Orgânica e Inorgânica, Federal University of Ceará, CEP: 60.440-900, Fortaleza, Ceará, Brazil

Mona Lisa Moura de Oliveira, State University of Ceará

Centro de Ciência e Tecnologia, State University of Ceará, CEP: 60741-000, Fortaleza, Ceará, Brazil

Francisco Sales Ávila Cavalcante, State University of Ceará

Centro de Ciência e Tecnologia, State University of Ceará, CEP: 60741-000, Fortaleza, Ceará, Brazil

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